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For example, ECM proteins crucial for cartilage structure and maintenance, such as ACAN, DCN, HSPG2, BGN, and FBLN1 were downregulated in the conditioned medium of H 2 O 2 -treated cells compared to those in control cells

Scorpion venom toxins consist of 2080 amino acids, contain 3-4 pairs of disulfide bonds, and have molecular weights ranging from 6,000 to 9,000 Da (Yang et al., 2020)

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Nrf2, a transcription factor, is typically inhibited by Keap1 under normal conditions

The foundational work describing the biological discovery of GHK and its role in tissue repair and regenerative signalling